LADIES LEUKEMIA LEAGUE
RESEARCH GRANT RECIPIENTS
1971-2017


1971-72 Charity Hospital $4,000.00
1972-73 Leukemia Society
Leukemia Trust Fund
$2,500.00
1974 Kathy McDaniel $350.00
Leukemia Society $3,233.66
Children's Hospital $590.00
Dr. William Barrios $2,500.00
Leukemia Society $1,244.52
Edgar Hull, M.D. $1,315.00
M.D. Anderson $1,500.00
1975 Jensie H. Tou $1,900.00
Dr. Robert Gallo $550.00
1976-77 Louisiana Cancer Center $500.00
1979 LSU Dept. of Pediatrics $1,100.00
Leukemia Society $1,972.00
Leukemia Society $3,000.00
1979-80 Leukemia Society $3,000.00
1980-81 Leukemia Society $4,980.00
1981-82 Leukemia Society $9,185.31
1981 Tulane $21,000.00
LSU $6,000.00
1981-83 Children's Hospital $13,000.00
1983 Dr. Schor $4,200.00
1983 Dr. S.H. Leech $4,490.00
1985-1989 Dr. Stephen P. Squntie
LSU
$17,500.00
Project: Human Recombinant Tumor Necrosis Factor Induction of Differentiation of Acute Lymphoblastic Leukemia Cells.

Dr. Emile Freireich
M.D. Anderson
$50,616.00
Project: Autologous Natural Killer (NK) Cell Therapy of Leukemia

Dr. Deborah A. Abertnathy
Tulane
$19,203.00
Project: In Vitro Effects of Retinoids and Recombinant Growth Factors on Normal and Myelodysplastic (Pre-leukemia) Hemopoietic Precursors and its Clinical Significance.


1989-90 Dr. Barbara Beckman
Tulane
$10,000.00
Project: Nuclear events in Leukemia Cells.


1990-92 Dr. Hung Yuen Yeh
LSU
$21,383.00
Project: The Usefulness of Soluble Interleukin-2 Receptor, Soluble CD8 Antigen and Protein Kinase C Activity in Childhood Acute Lymphoblastic Leukemia.
Comment: Seven patients with acute lymphoblastic leukemia were entered on the study and have been followed up for a minimum of 15 months and a maximum of 24 months.

A manuscript has been written on the first five patients and submitted for publication.

Dr. R.P. Warrier
LSU
$30,000.00
Project: Research of childhood leukemia.

Dr. Albert Desserath
M.D. Anderson
$50,000.00
Project: Moleculr Approaches to the Therapy of Leukemia
Comment: Published in The Journal of Biological Chemistry.

Dr. James R. Jeter
Tulane
$21,200.00
Project: Molecular Events in the Regulation of Hematopoiesis

Dr. Cindy Leissenger
Tulane
$21,660.00


1993-94 Dr. Marion Feistadt
LSU
$20,764.00
Project: A Simple and Novel Protocol to Identify the HTLV-1 Cell Surface Receptor.
Comment: Received a grant from the Cancer Association of Greater New Orleans to continue project.


1994-95 Dr. Wayne Vedecksi
LSU
$23,000.00
Project: "Characterization of p90, a new marker for acute Promyelocylic Leukemia".
Comment: "We have succeeded in implementing the RT-PCR assay for acute promyelocytic leukemia (APL) in our lab. We have followed an APL patient for two years, and the assay results agree with the clinical course of the disease".

Dr. Laura Levy
Tulane
$22,500.00
Project: Molecular Determinants of Lymphoid Malignancy
Comment: This project appeared in four publications, including the Journal of Virology and the International Journal of Cancer.

Dr. David J. Carr
LSU
$20,959.00
Project: Aberrant Regulation of Cytokines in HIV-1 TAT72 Transgenic Mice.
Comment: Published in The Journal of Immunology.

Dr. Michael Andreeff
M.D. Anderson
$20,800.00
Project: Leukemia
Comment: The result of this project was presented at the Annual Meeting of the American Society of Hematology. This project was published in the Blood Journal


.
1995-96 Dr. Ronald Luftig
LSU
$23,200.00
Project: Actin Cytoskeleton in Leukemia Virus Morphogenesis
Comment: This abstract was presented at the Annual Meeting of the American Society for Virology.

Dr. Rene Gardner $29,000.00
Project: Long-Term Hemopoietic Injury Induced by Chemotherapy

FILE MISSING $31,700.00


1996-97 Dr. Madeleine Duvic
Univ. of Texas-Houston
$37,500.00
Project: Pathenogeneis of Sezary Syndrome
Comment: This project was published in The Journal Blood.

Dr. Jiandong Chen
LSU
$21,995.00
Project: The Proleolytic Cleavage of the md m 2 Oncogene Product Dureng p52 mediated Apoptosis.

Dr. Maria Velez-LSU $24,000.00
Project: Efficacy of Corticosteroid Treatment in Primary and Relapse Leukemia Patients: Role of Glucocorticoid Receptor Gene.
Comment: Collaborating with the University of Mississippi and Children's Hospital in Los Angeles, Michigan and Tampa.

Dr. Barbara Beckman
Tulane
$14,800.00
Project: The Molecular Mechanism of Multidrug Resistance in Leukemia.
Comment: This project appeared in two journals.


1997-98 Dr. Eric S. Johnson
Tulane
$40,540.00
Project: Detection of Avian Leukosis/Sarcoma Viruses (ALSV) in the Genome of Human Leukemia and Lymphoma Tumor Cells.
Comment: As a result of the preliminary findings he recently was awarded a two-year grant from the NIH.

Jorge Cortes, M.D.
M.D. Anderson
$42,800.00
Project: Immune Recognition OF p210 Cra/Abl in Patients with Chronic Myelogenous Leukemia.
Comment: Significant progress in the identification of specific immune recognition of p210 BCR/ABL, both by cellular and humoral mechanisms, and correlation with response to Interferon treatment.

Dr. Paul Schwarzenberger
LSU
$19,880.00
Project: Development of a gene therapy based bone marrow purging system for leukemia patients.


1998-99 David Good, M.D.
LSU
$30,000.00
Project: Selective Targeting of Hematopoietic Stem Cells via the c-kit Receptor.

Patricia D. Castro, Ph.D. and Lalitha Nagarajan, Ph.D
M.D. Anderson
$33,000.00
Project: Deletions of chromosome 5Q 13.3 and 17p loci cooperate in myeloid neopla.
Comment: Received honorable mention in the Bristol-Myers Squibb Award in Clinical/Translational Science. This project was published in the March 1999 issue of BLOOD JOURNAL. Applied for an $800,000 federal grant on this project. The review is quite favorable.

Chris Theodossiou, M.D.
LSU
$45,540.00
Project: Investigation of IL 17 in Patients with Bone Marrow Failure.

Laura Levy, Ph.D. $19,500.00
Project: Role of the Immune Environment in the Development of Lymphoma.
Comment: The results were published in a manuscript by Beaty, R.M., K. Rulli, L. Bost, J. Pantginis, J. Lenz and L.S. Levy, L99 high levels of Il-4 and 11-10mRNA and low levels of Il-2 and IFN-Yymrna in MuL V-induced lymphomas. Published in GENE (An International Journal on Genes, Genomes and Evolution): Identification and analysis of a third mouse Polycomb gene MPC3. Received additional funding from American Cancer Society and Development Funds from the Tulane Cancer Center.


1999-2000 Marina Konopleva, M.D. Ph.D.
M.D. Anderson
$58,724.00
Project: Therapy of AML.
Comment: Submitted to NCI. Preliminary results obtained have assisted in being awarded the W.M. Keck Foundation Grant at the University of Texas, M.D. Anderson Center "Anti-apoptotic Protein Survivin as a New Target in AML Therapy". The research conducted under this grant award also assisted in renewing an NCI grant award.

Charles S. Hemenway, M.D., Ph.D.
Tulane
$10,000.00
Project: Analysis of a third mouse Polycomb gene, MPc3
Comment: Paper published in GENE (An International Journal on Genes, Genomes and Evolution) on protocol Identification and Analysis of a Third Mouse Polycomb gene, MPc3.

Kevin D. Brown, Ph.D.
LSU
$34,550.00
Project: ATM KINANSE DOMAI
Comment: This project was submitted to the journal Biotechniques. A grant request was made to NIH for this project. This project established a new avenue of investigation (colon cancer gene). A manuscript is being published at this time.


2000-2001 Richard H. Scheurmann, Ph.D
UT Southwest Medical Center, Dallas
$49,500.00
Project: Targeting Peptides for T-Cell Acute Lymphoblastic Leukemia Therapy.
Comment: Seeking additional funding to continue the project.

Guillermo Garcia-Manero, M.D
M.D. Anderson
$40,000.00
Project: "Post-remission immunotherapy of acute myelogenous leukemia with an autologous dinitrophenyl (DNP)-modified leukemia cell vaccine".
Comment: This study has allowed us to better understand the theraputic needs of patients with advance AML and potentially develop similar programs for patients in first remission or after allogeneic bone marrow transplantation.

Reeves Huie, Ph.D.
M.D. Anderson
$35,000
Project: Evaluation of Plasma 5-Oxoprolime as a Convenient Marker of Apoptosis in Leukemia
Comment: Grant funds were returned. Dr. Huie left M.D. Anderson before project was started.


2001-2002 Francesco Onida, M.D.
M.D. Anderson
$30,000.00
Project: Development of New Combination Therapies for Philadelphia Chromosome Positive Leukemia
Comment: Submitted project to the Cancer publication. Result of this study was presented at the Annual Meeting of the American Society of Hematology.

Renee V. Gardner, M.D.
LSU
$29,742.00
Project: A Study of Rasayanas as a Cardioprotectant Agent Through Antioxidation

Laura Levy, Ph.D.
Tulane
$34,989.00
Project: Clinical and Laboratory Predictors of Lymphoma in the Nonhuman Primate Model.

Angus McLeod Sinclair, Ph.D.
UT, Dallas
$35,000.00
Project: Role of Transcriptional Repressor CDP in myeloid Leukemia.

Li Li, M.D. Ph.D.
Ochsner
$30,000.00
Project: Stromal Cell Molecules Required for Malignant-B Cell Tumor Generation in Vivo.


2002-2003 Dr. Bing Z. Carter
M.D. Anderson
$35,000.00
Project: "Target Antiapoptotic Survivin in Acute Myelogenous Leukemia."

Laura Levy, Ph.D.
Tulane
$35,000.00
Project: Growth Regulations of SAIDS-Associated Lymphomas

Dr. Srdan Verstovsek
M.D. Anderson
$30,000.00
Project: "Targeted Anti-Angiogenesis Therapy of Myeloid Bone Marrow Diseases."

Dr. Mansour Mohamadzadeh
Tulane
$30,000.00
Project: Development of a Novel Il-15 Based Vaccine to Treat Cutaneous T Cell Lymphoma.
Dr. Yan Cui
LSU
$30,000.00
Project: Empower the Immune System to Combat Leukemia: Combination Immunotherapy of Targeting Tumor Antigen to Dendritic Cella and GM-CSF Enchanced Antigen Presentation.


2003-2004 Seth J. Corey, M.D. MPH
M.D. Anderson
$30,000.00
Project: "siRNA Tareting of Lyn Tyrosine Kinase in Acute Leukemia"

Bulent Ozspolat, M.D., Ph.D.
M.D. Anderson
$32,500.00
Project:"Identification of Novel Molecular Targets in All-Transretinoic Acid (ATRA) Induced Differentiation and Resistance in Acute Promyeloctic Leukemia Through Expression Proteomics Analysis"

Frank C. Marini, Ph.D.
M.D. Anderson
$30,000.00
Project: "Mesenchymal Stem Cells (Stromal Cells) Expressing Interferon as a Targeted Antileukemia Therapy"

Charles S. Hemenway, M.D., Ph.D.
Tulane University School of Medicine
$34,187.00
Project: "Development of a Model of Infant Leukemia for Targeted Therapeutics"


2004-2005 Bing Z. Carter, Ph.D
M.D. Anderson
$35,000.00
Project: "The X-chromosome-linked Inhibitor of Apoptosis as a Therapeutic Target for the Treatment of Acute Myeloid Leukemia"
Laura S. Levy, Ph.D.
Tulane University School of Medicine
$35,000.00
Project: "Novel Retroviruses as Tools for the Discovery of Oncogenes Associated with Lymphoma"
Bo Xu, M.D., Ph.D.
LSU Health Sciences Center
$35,000
Project:"Interfering with DNA Damage Signals: Chemo-sensitizing Leukemia Using Small Peptides"


2005-2006 Erik K. Flemington, Ph.D.
Tulane Health Sciences Center, Department of Pathology, SL79
$25,000.00
Project:"Identification of EBV regulated cellular genes that contribute to EBV associated lymphomas"
Soung-Chul Cha, Ph.D., M.D
University of Texas, MD Anderson Cancer Center
$25,000.00
Project: "Discovering novel lymphoma antigens as targets for immunotherapy"
Xiao Ni, M.D. Ph.D.
University of Texas, MD Anderson Cancer Center
$25,000
Project:"Induction of Polyclonal T-Cell Responses against Cutaneous T-Cell Lymphomas by Autologous Dendritic Cells Transfected with Amplified Tumor RNA"
Mary Ann Weiser, M.D. Ph.D.
University of Texas, MD Anderson Cancer Center
$25,000.00
Project: "Effects of hyperglycemia and AKT Activation on Chemo Resistance of Blasts from Patients with Acute Lymphocytc Leukemia"
Rui-Yu Wang, M.D., Ph.D.
University of Texas, MD Anderson Cancer Center
$25,000
Project:"The Role of Apoptotic Inducing Factor (AIF) IN Acute Myeloid Leukemia"


2007-2008 Terzah M. Horton, M.D. Ph.D.
Texas Children's Cancer Center, Baylor College of Medicine
$30,000.00
Project:Targeting Pediatric Leukemia Stem Cells to Enhance Treatment Response rates
Marilyn M. Li, M.D.
Tulane University Health Science Center, Hayward Genetics Center
$30,000.00
Project: MLL partial tandem duplications in prenatal tissues and cord blood: Benign Micro-mosaicism or Laten Predisposition
Xin Lin, Ph.D.
University of Texas, MD Anderson Cancer Center, Associate Professor, Department of Molecular and Cellular Oncology
$30,000.00
Project:CARMA 1 (a scaffold molecule) - associated NF-AF activation in diffuse large B cell lymphoma
2008-2009 Shuo Dong, M.D., Ph.D
Baylor College of Medicine
$33,500.00
Project: Histone Demethylase RADMI in the Pathogenisis of Acute Promyelocytic Leukemia
LiLi, M.D., Ph.D
Cellular Immunology Dept, Ochsner Clinic Foundation
$35,000.00
Project: Identification o B-Cell Lymphoma Stem Cells and their Microenvironmental Factors
Paulo C. Rodriguez, Ph.D.
LSU Health Science Center
$35,000.00
Project:Project: L-Arginine Availability Regulates Proliferation of Malignant T-Cells
Amos Gaikwad, Ph.D
Baylor College of Medicine
$35,000.00
Project: Study of novel therapeutic Agents to Target the Leukemic Stem Cells
Ajoy Kumar Samanta, Ph.D.
M.D. Anderson Cancer Center
$35,000.00
Project: Therapeutic Evaluation of New Small Molecule WP1193 Targeting Bcr-Abl Driven JAK-STAT Pathway for Treatment of Imatinib Resistant Chronic Myelogenous Leukemia


2009-2010 M. James You, M.D., Ph.D.
Assistant Professor, The University of Texas M.D. Anderson Cancer Center
$35,000.00
Project: Generation and Characterization of T-all with Deficiency in Pten and Ink4A/ARF Tumor Suppressors.
Felipe Samaniego, M.D.
The University of Texas M.D. Anderson Cancer Center
$35,000.00
Project: Targeting of FAS Inhibitor CD 74 in Human Chronic Lymphocytic Leukemia (CLL) with anti-CD74 antibody.
Xiaoping Sun, M.D., Ph.D.
The University of Texas M.D. Anderson Cancer Center
$35,000.00
Project:Project: Role of SOX4 in the interaction between Leukemic Cells and Bone Marrow Niches
Laura S. Levy, Ph.D.
Tulane University School of Medicine
$35,000.00
Project: Protien Kinase C-beta (PKCB) as a Potential Therapeutic Target in Lymphoma.
Deepa Sampath, Ph.D.
The University of Texas M.D. Anderson Cancer Center
$35,000.00
Project: Targeting Epigenetically-silenced MicroRNA Pathways for the therapy of Chronic Lymphocytic Leukemia.
Lynne V. Abruzzo, M.D., Ph.D.
The University of Texas M.D. Anderson Cancer Center
$35,000.00
Project: Genomic Evolution in Patients with Chronic Lymphocytic Leukemia Treated With FCR Chemoimmunotherapy.
2010-2011 Laurance J.N. Cooper, M.D., Ph.D.
The University of Texas M.D. Anderson Cancer Center
$35,000.00
Project: Immune-based Therapy for Malignant T Cells.
Erik Flemington, Ph.D.
Tulane Health Sciences Center
$35,000.00
Project: Targetome Analysis of Epstein Barr (EBV) encoded mcroRNAs
Shuo Dong, M.D.
Baylor College of Medicine
$35,000.00
Project: Targeting STAT3 Pathway in the Suppression of MLL Fusion Protein Mediated Transformation
Michele Redell, M.D., Ph.D.
Baylor College of Medicine
$35,000.00
Project: Understanding and Overcoming Chemotherapy Resistance in Pediatric Acute Myeloid Leukemia
2011-2012 Tara L. Lin, M.D.,
LSU Health Sciences Center
$35,000.00
Project: Chemotherapy resistance in Acute Lymphocytic Leukemia: the role of Hedgehog pathway signaling


Yu-Ping Wang
Tulane University
$35,000.00
Project: Bioinformatics technique for accurate subtype classification of myelodysplastic syndrome (MDS).

Xiao-Tong Song, Ph.D.
Baylor College of Medicine
$35,000.00
Project: Tumor Stroma-Targeted Dendritic Cell Vaccine for B cell Lymphoma

M. James You, MD, Ph.D.
MD Anderson Cancer Center
$35,000.00
Project: Role of ECRGA in Acute Myeloid Leukemia

Bryant G. Damay, Ph.D.
MD Anderson Cancer Center
$35,000.00
Project: Evaluation of TAK1 as a New Tumor Suppressor Gene for Myeloid Leukemia





2012-2013 Shuo Dong, M.D., Ph.D.
Baylor College of Medicine
$35,000.00
Project: Histone demethylase function as tumor suppressor in MLL-mediated leukemogenesis


Karen Rabin, M.D., Ph.D.
Baylor College of Medicine
$35,000.00
Project: Discovery of Novel Therapeutic Targets in Acute Lymphoblastic Leukemia by shRNA


Laura S. Levy, Ph.D.
Tulane University School of Medicine
$35,000.00
Project: Beta-Catenin Accumulation as an Apoptotic Signal in B-cell Acute Lymphoblastic Leukemia


Lily Jun-shen Huang, Ph.D.
UT Southwestern Medical Center
$35,000.00
Project: Identify and characterize leukemic stem cells in myeloproliferative neoplasms


Alfonso Quintas-Cardama, M.D.
The University of Texas MD Anderson Cancer Center
$35,000.00
Project: Therapy with novel CBP-beta-Catenin inhibitor PRI-724 for the Cure of Patients with Chronic Myeloid Leukemia Carrying Minimal residual Disease while on Therapy with Tyrosine Kinase Inhibitors
2013-2014

 

Hua Lu, MD, PhD $35,000
Tulane University School of Medicine
Project: Preclinical Evaluation of a Novel Small Molecule “Inauhzin-37” as Potential
Leukemia/lymphoma Therapy

Joseph A. Lasky, MD $25,000
Tulane University School of Medicine
Project: The use of Arsenic Trioxide and Ganciclovir in the Induction of Apoptosis In Epstein-Barr Driven Primary Lymphoma Cell Lines and in an in vivo Model of Post-transplant Lymphoproliferative Disease

LiLi, MD, PhD $25,000
Tom Benson Cancer Center
Project: Identification of Prognostic Markers in Follicular Lymphoma
 
Zhihong Zeng, MD
MD Anderson Cancer Center
Project: Investigating the molecular of microenvironment-mediated drug resistance in leukemia stem cells by CyTOF mass cytometry
 
2014-2015 Zhiqiang Qin, MD, PhD  - $30,000
LSU Health Sciences Center – New Orleans
PROJECT: The role of HGF/c-MET Pathway in AIDS-related Lymphoma

Stephen Gottschalk, MD - $35,000
Baylor College of Medicine
PROJECT: T-cell Therapy for Acute Myelogenous Leukemia

Sean M. Post, PhD - $35,000
MD Anderson Cancer Center
PROJECT: hnPNP K expression and leukemia: Walking the tightrope

Jinsheng Weng, PhD - $35,000
The University of Texas
Project: Targeting CLL and through tumor antigen specific T cells

2015-2016 Hua Lu, MD, PhD $30,000
Tulane University School of Medicine
PROJECT: Targeting GRP78 by PNIN as Potential and Novel Leukemia/lymphoma Therapy

Thomas Keen, PhD $35,000
Baylor College of Medicine
PROJECT: Improved engraftment of umbilical cord blood stem cells using a bone marrow targeting peptide.

Alessandra Ferrajoli, MD $30,000
MD Anderson Cancer Center
Project: Clinical and Genomic Studies of Other Cancers in Patients with Chronic Lymphocytic Leukemia.

Weiguo Zhang, MD, PhD $30,000
MD Anderson Cancer Center
Project: Mechanism-based combinatorial Strategy for targeting leukemic-initiating cells in relapsed acute myeloid leukemia with FLT3/ITD mutations
2016-2017

Nakhle Saba, MD – Tulane University School of Medicine - $27,000

Project:  Investigating the Role of the Novel RELA E39Q Mutation in Mantle Cell Lymphoma

Zachary Prsell, PhD – Tulane University School of Medicine - $27,000

Project:  Characterization of Novel Biomarkers of therapy-related AML/MDS 

Courtney DiNardo, MDE – MD Anderson Cancer Center - $27,000

Project:  Evaluation of D-2HG levels in AML patients with 1DH1 and/or IDH2 mutations receiving therapy 

Janos Roszik and Naval Daver – MD Anderson Cancer Center - $27,000

Project:  Identification of novel immunotherapy targets for AML using computational genomics and mass spectrometry

 





BACK





Ladies Leukemia League, Inc.
P.O. Box 9355
Metairie, LA 70055-9355
I.D.# 72-0997410